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muscularis externa submucosal layer filled with Peyer`s patches muscularis mucosa mucosal layer with columnar epithelium (many of which are goblet cells) intestinal lumen muscularis mucosa submucosal layer (filled with Peyer`s patches) intestinal crypts (crypts of Lieberkuhn) intestinal crypts (crypts of Lieberkuhn) villi with columnar cells many of which are goblet cells (villi are filled with lamina propria) villi with columnar cells many of which are goblet cells (villi are filled with lamina propria) fragments of a villus fragments of a villus